第二届语言康复在举行

时间:2020-05-25 20:16:59 作者:258369147114 热度:1199℃

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(国)(内)(约)180(家)(企)(业)(布)(局) (生)(物)(类)(似)(药)(大)(战)(一)(触)(即)(发)|||||||

(()(原)(标)(题)(:)(国)(内)(约)180(家)(企)(业)(布)(局) (生)(物)(类)(似)(药)(大)(战)(一)(触)(即)(发)())

(多)(个)(生)(物)(制)(剂)(大)(品)(种)(专)(利)(到)(期)(,)(全)(球)(生)(物)(类)(似)(药)(规)(模)(进)(入)(快)(速)(增)(长)(阶)(段)(,)(而)(中)(国)(拥)(有)(全)(球)(数)(量)(最)(多)(的)(生)(物)(类)(似)(药)(研)(发)(管)(线)(。)(恒)(瑞)(医)(药)(、)(绿)(叶)(制)(药)(贝)(伐)(珠)(单)(抗)(的)(上)(市)(申)(请)(于)(近)(日)(相)(继)(获)(得)(受)(理)(,)(市)(场)(竞)(争)(一)(触)(即)(发)(。)

4(款)(国)(产)(生)(物)(类)(似)(药)(获)(批)

(生)(物)(类)(似)(药)(,)(是)(指)(在)(质)(量)(、)(安)(全)(性)(和)(有)(效)(性)(方)(面)(与)(已)(获)(准)(注)(册)(的)(参)(照)(药)(具)(有)(相)(似)(性)(的)(治)(疗)(用)(生)(物)(制)(品)(,)(也)(被)(称)(为)(生)(物)(仿)(制)(药)(。)2015(年)2(月)28(日)(,)(《)(生)(物)(类)(似)(药)(研)(发)(与)(评)(价)(技)(术)(指)(导)(原)(则)(()(试)(行)())(》)(发)(布)(,)(首)(次)(明)(确)(了)(生)(物)(类)(似)(药)(的)(定)(义)(,)(提)(出)(了)(生)(物)(类)(似)(药)(研)(发)(和)(评)(价)(的)(基)(本)(原)(则)(等)(多)(方)(面)(内)(容)(。)

(近)(年)(来)(,)(生)(物)(药)(快)(速)(发)(展)(,)(并)(在)(治)(疗)(一)(些)(疾)(病)(方)(面)(显)(示)(出)(明)(显)(的)(临)(床)(优)(势)(。)(随)(着)(原)(研)(生)(物)(药)(专)(利)(到)(期)(及)(生)(物)(技)(术)(的)(不)(断)(发)(展)(,)(以)(原)(研)(生)(物)(药)(质)(量)(、)(安)(全)(性)(和)(有)(效)(性)(为)(基)(础)(的)(生)(物)(类)(似)(药)(的)(研)(发)(,)(有)(助)(于)(提)(高)(生)(物)(药)(的)(可)(及)(性)(和)(降)(低)(价)(格)(,)(满)(足)(群)(众)(用)(药)(需)(求)(。)(据)(弗)(若)(斯)(特)(沙)(利)(文)(报)(告)(,)2014(年)(全)(球)(生)(物)(类)(似)(药)(的)(规)(模)(为)17(亿)(美)(元)(,)2018(年)(达)(到)(了)72(亿)(美)(元)(,)(预)(计)2030(年)(将)(达)(到)1644(亿)(美)(元)(。)(随)(着)(我)(国)(药)(企)(研)(发)(水)(平)(的)(提)(升)(及)(政)(策)(的)(放)(开)(,)(我)(国)(生)(物)(类)(似)(药)(近)(年)(来)(发)(展)(迅)(猛)(。)

(截)(至)(目)(前)(,)(中)(国)(已)(有)4(款)(国)(产)(生)(物)(类)(似)(药)(在)2019(年)(先)(后)(获)(批)(上)(市)(。)2019(年)2(月)(,)(复)(宏)(汉)(霖)(的)(利)(妥)(昔)(单)(抗)(注)(射)(液)(()(商)(品)(名)(:)(汉)(利)(康)())(获)(批)(,)(成)(为)(我)(国)(首)(个)(获)(批)(的)(生)(物)(类)(似)(药)(。)(利)(妥)(昔)(单)(抗)(由)Genentech(公)(司)(()(后)(被)(罗)(氏)(收)(购)())(研)(发)(,)(商)(品)(名)(“)(美)(罗)(华)(”)(,)(是)(美)(国)FDA(批)(准)(的)(首)(个)(用)(于)(治)(疗)(癌)(症)(的)(单)(克)(隆)(抗)(体)(,)(也)(是)(全)(球)(最)(畅)(销)(的)(单)(抗)(类)(药)(物)(之)(一)(。)

2019(年)11(月)7(日)(,)(百)(奥)(泰)(自)(主)(开)(发)(的)(阿)(达)(木)(单)(抗)(注)(射)(液)(()(商)(品)(名)(“)(格)(乐)(立)(”)())(获)(批)(上)(市)(,)(是)(国)(内)(首)(个)(获)(批)(的)(阿)(达)(木)(单)(抗)(生)(物)(类)(似)(药)(。)(该)(药)(原)(研)(药)(修)(美)(乐)(由)(艾)(伯)(维)(研)(发)(,)(于)2010(年)(获)(批)(上)(市)(,)(被)(称)(为)(全)(球)(“)(药)(王)(”)(,)(其)(销)(售)(额)(曾)(连)(续)7(年)(蝉)(联)(全)(球)(处)(方)(药)(销)(售)(冠)(军)(,)(上)(市)(至)(今)(累)(计)(销)(售)(额)(超)1000(亿)(美)(元)(。)2019(年)12(月)6(日)(,)(海)(正)(药)(业)(阿)(达)(木)(单)(抗)(注)(射)(液)(()(商)(品)(名)(:)(“)(安)(建)(宁)(”)())(也)(获)(批)(上)(市)(。)

(就)(在)(同)(一)(天)(()2019(年)12(月)6(日)())(,)(齐)(鲁)(制)(药)(的)(贝)(伐)(珠)(单)(抗)(注)(射)(液)(()(商)(品)(名)(:)(“)(安)(可)(达)(”)())(也)(获)(批)(上)(市)(,)(成)(为)(国)(内)(首)(个)(获)(批)(的)(贝)(伐)(珠)(单)(抗)(生)(物)(类)(似)(药)(,)(原)(研)(药)(为)(罗)(氏)(的)(“)(安)(维)(汀)(”)(。)(安)(维)(汀)(是)(罗)(氏)(的)(重)(磅)(抗)(肿)(瘤)(产)(品)(,)(据)(全)(球)(畅)(销)(药)(数)(据)(统)(计)(,)(该)(药)(销)(售)(额)(在)2005(年)(突)(破)10(亿)(美)(元)(大)(关)(,)(随)(后)(的)(销)(售)(额)(成)(倍)(增)(长)(,)2019(年)(销)(售)(额)(已)(经)(高)(达)74.94(亿)(美)(元)(,)(总)(销)(售)(额)(累)(计)(近)859(亿)(美)(元)(。)(由)(于)(该)(药)(专)(利)(期)(在)(欧)(美)(于)2018(年)(和)2019(年)(先)(后)(到)(期)(,)(成)(为)(热)(门)(仿)(制)(产)(品)(。)

(原)(研)(药)(市)(场)(受)(到)(巨)(大)(冲)(击)

(生)(物)(类)(似)(药)(获)(批)(上)(市)(,)(对)(原)(研)(药)(市)(场)(造)(成)(巨)(大)(冲)(击)(。)(如)(利)(妥)(昔)(单)(抗)(,)(受)(生)(物)(类)(似)(药)(上)(市)(影)(响)(,)(美)(罗)(华)(全)(球)(销)(售)(额)(出)(现)(下)(滑)(。)(罗)(氏)(在)2019(年)(一)(季)(报)(中)(提)(及)(,)(受)(生)(物)(仿)(制)(药)(影)(响)(,)(美)(罗)(华)(在)(欧)(洲)(市)(场)(销)(售)(额)(下)(滑)38%(,)(日)(本)(市)(场)(下)(滑)50%(;)(而)2019(年)(全)(球)(销)(售)(额)(下)(滑)4%(。)

(中)(国)(市)(场)(上)(,)(汉)(利)(康)(也)(在)(以)(低)(价)(政)(策)(争)(夺)(美)(罗)(华)(的)(市)(场)(。)2019(年)7(月)30(日)(,)(贵)(州)(省)(医)(药)(集)(中)(采)(购)(平)(台)(发)(布)(公)(告)(,)(同)(意)(复)(宏)(汉)(霖)(将)(汉)(利)(康)(的)(价)(格)(由)1640(元)/(瓶)(调)(整)(为)1398(元)/(瓶)(,)(降)(幅)15%(。)(而)(美)(罗)(华)(同)(品)(规)(的)(价)(格)(为)2294.44(元)(。)4(月)24(日)(,)(复)(星)(医)(药)(发)(布)(的)(公)(告)(显)(示)(,)2019(年)(,)(汉)(利)(康)(于)(中)(国)(大)(陆)(境)(内)(的)(销)(售)(额)(约)(为)1.5(亿)(元)(。)

(对)(于)(阿)(达)(木)(单)(抗)(()(修)(美)(乐)())(而)(言)(,)(未)(来)(日)(子)(更)(不)(好)(过)(。)(被)(称)(为)(全)(球)(“)(药)(王)(”)(的)(修)(美)(乐)(,)(在)(欧)(盟)(地)(区)(遭)(遇)4(款)(生)(物)(类)(似)(药)(上)(市)(围)(堵)(,)(其)2019(年)(销)(售)(额)(相)(较)(其)(峰)(值)(时)(期)(下)(降)(了)(近)8(亿)(美)(元)(。)(而)(修)(美)(乐)(在)(中)(国)(市)(场)(的)(销)(售)(额)(则)(一)(直)(很)(惨)(淡)(,)(艾)(美)(达)(数)(据)(显)(示)(,)2018(年)(,)(修)(美)(乐)(在)(中)(国)(样)(本)(公)(立)(医)(院)(和)(样)(本)(连)(锁)(药)(店)(的)(销)(售)(额)(分)(别)(仅)(有)2120(万)(元)(和)1460(万)(元)(。)(获)(批)(适)(应)(症)(少)(、)(价)(格)(高)(、)(未)(进)(国)(家)(医)(保)(目)(录)(等)(原)(因)(是)(其)(此)(前)(国)(内)(市)(场)(“)(遇)(冷)(”)(的)(主)(要)(原)(因)(,)(其)(在)(中)(国)(患)(者)(中)(的)(使)(用)(率)(不)(到)1%(。)(而)(彼)(时)(,)(国)(内)(已)(有)(多)(家)(企)(业)(在)(研)(发)(阿)(达)(木)(单)(抗)(生)(物)(类)(似)(药)(。)

(面)(对)(虎)(视)(眈)(眈)(的)(潜)(在)(竞)(争)(者)(,)2019(年)(年)(中)(,)(修)(美)(乐)(开)(启)(了)(降)(价)(之)(路)(,)(单)(价)(从)7600(元)(调)(整)(至)3160(元)(,)(降)(幅)(近)60%(。)2019(年)11(月)28(日)(,)(阿)(达)(木)(单)(抗)(成)(功)(进)(入)2019(年)(医)(保)(谈)(判)(目)(录)(,)(修)(美)(乐)(医)(保)(支)(付)(标)(准)(为)1290(元)(。)(与)(修)(美)(乐)(的)(医)(保)(支)(付)(价)(格)(相)(比)(,)(百)(奥)(泰)(的)(格)(乐)(立)(和)(海)(正)(药)(业)(的)(安)(建)(宁)(在)(价)(格)(上)(仍)(略)(有)(优)(势)(,)(新)(京)(报)(记)(者)(在)(米)(内)(网)(数)(据)(库)(看)(到)(,)(两)(个)(国)(产)(药)(同)(品)(规)(的)(医)(保)(支)(付)(价)(格)(分)(别)(为)1160(元)(、)1150(元)(。)

(贝)(伐)(珠)(单)(抗)(也)(面)(临)(同)(样)(局)(面)(。)2017(年)(,)(安)(维)(汀)(以)(近)60%(的)(价)(格)(降)(幅)(进)(入)(国)(家)(乙)(类)(医)(保)(目)(录)(,)(价)(格)(为)1998(元)(,)2018(年)(进)(一)(步)(降)(至)1934(元)(。)(米)(内)(网)(数)(据)(显)(示)(,)(今)(年)(在)(福)(建)(省)(,)(齐)(鲁)(制)(药)(安)(可)(达)(的)(中)(标)(价)(为)1198(元)(,)(比)(原)(研)(药)(安)(维)(汀)(的)(价)(格)(便)(宜)(了)700(余)(元)(。)(新)(思)(界)(产)(业)(研)(究)(中)(心)(发)(布)(的)(《)2019-2023(年)(贝)(伐)(珠)(单)(抗)(行)(业)(深)(度)(市)(场)(调)(研)(及)(投)(资)(策)(略)(建)(议)(报)(告)(》)(指)(出)(,)(我)(国)(贝)(伐)(珠)(单)(抗)(受)(众)(群)(体)(较)(少)(,)(市)(场)(规)(模)(较)(小)(,)(原)(研)(药)(竞)(争)(优)(势)(不)(明)(显)(,)(随)(着)(生)(物)(类)(似)(药)(上)(市)(,)(凭)(借)(其)(较)(高)(的)(性)(价)(比)(优)(势)(,)(市)(场)(占)(有)(率)(将)(迅)(速)(扩)(张)(。)(未)(来)(三)(年)(内)(,)(我)(国)(进)(入)(市)(场)(的)(贝)(伐)(珠)(单)(抗)(生)(物)(类)(似)(药)(种)(类)(将)(不)(断)(增)(多)(,)(而)(率)(先)(进)(入)(市)(场)(的)(国)(内)(企)(业)(将)(优)(先)(受)(益)(。)

(国)(内)(近)400(个)(研)(发)(管)(线)

(中)(金)(研)(报)(指)(出)(,)(中)(国)(生)(物)(类)(似)(药)(市)(场)(规)(模)(有)(望)(呈)(现)(爆)(发)(式)(增)(长)(。)2018(年)(中)(国)(生)(物)(类)(似)(药)(市)(场)(规)(模)(仅)16(亿)(元)(,)2014(年)-2018(年)(年)(均)(复)(合)(增)(长)(率)(为)18.9%(。)(生)(物)(类)(似)(药)(研)(发)(成)(本)(更)(低)(,)(因)(此)(更)(具)(价)(格)(优)(势)(。)(随)(着)(中)(国)(逐)(渐)(建)(立)(生)(物)(类)(似)(药)(监)(管)(审)(批)(路)(径)(、)(医)(保)(资)(金)(成)(本)(控)(制)(加)(强)(、)(中)(国)(企)(业)(制)(造)(能)(力)(提)(升)(以)(及)(大)(量)(知)(名)(生)(物)(制)(剂)(的)(专)(利)(即)(将)(到)(期)(等)(因)(素)(,)(中)(国)(生)(物)(类)(似)(药)(市)(场)(规)(模)(将)(于)2030(年)(达)(到)589(亿)(元)(,)2018(年)-2030(年)(年)(均)(复)(合)(增)(长)(率)(预)(计)(为)35.1%(。)

(虽)(然)(中)(国)(批)(准)(的)(生)(物)(类)(似)(药)(数)(量)(目)(前)(只)(有)4(款)(,)(但)(是)(研)(发)(管)(线)(数)(量)(却)(是)(全)(球)(最)(多)(,)(国)(内)(药)(企)(都)(在)(加)(速)(研)(发)(。)(据)(药)(渡)(数)(据)(库)(统)(计)(,)(截)(至)2019(年)12(月)(,)(中)(国)(生)(物)(类)(似)(药)(研)(发)(管)(线)(数)(量)(约)(有)391(个)(,)(约)(有)180(家)(企)(业)(在)(布)(局)(生)(物)(类)(似)(药)(,)(主)(要)(靶)(点)(包)(括)CD20(、)EFGR(、)VEGF(、)TNF(、)RANKL(、)HER2(等)(,)(涉)(及)(利)(妥)(昔)(单)(抗)(、)(曲)(妥)(珠)(单)(抗)(、)(贝)(伐)(珠)(单)(抗)(、)(阿)(达)(木)(单)(抗)(等)50(余)(款)(原)(研)(药)(物)(,)(先)(后)(已)(有)(近)200(余)(个)(生)(物)(类)(似)(药)(的)(临)(床)(试)(验)(申)(请)(获)(批)(。)(业)(内)(根)(据)(目)(前)(中)(国)(生)(物)(类)(似)(药)(的)(平)(均)(开)(发)(和)(上)(市)(审)(评)(时)(间)(预)(测)(,)(未)(来)3(年)(将)(会)(有)(近)30(款)(国)(产)(生)(物)(类)(似)(药)(获)(批)(上)(市)(,)(其)(中)(今)(年)(预)(计)(有)6(款)(获)(批)(。)

(以)(国)(内)(获)(批)(数)(量)(最)(多)(的)(贝)(伐)(珠)(单)(抗)(为)(例)(,)(国)(产)(生)(物)(类)(似)(药)(方)(面)(,)(至)(少)(有)20(多)(家)(企)(业)(在)(布)(局)(,)(除)(了)(齐)(鲁)(制)(药)(的)(安)(可)(达)(已)(获)(批)(上)(市)(,)(信)(达)(生)(物)(的)(贝)(伐)(珠)(单)(抗)(上)(市)(申)(请)(早)(在)2019(年)1(月)(就)(已)(经)(获)(受)(理)(,)(今)(年)4(月)(,)(恒)(瑞)(医)(药)(、)(绿)(叶)(制)(药)(提)(交)(的)(上)(市)(申)(请)(相)(继)(获)(受)(理)(,)(安)(维)(汀)(很)(快)(将)(迎)(来)(多)(个)(新)(对)(手)(。)(另)(外)(,)(百)(奥)(泰)(、)(东)(曜)(药)(业)(、)(华)(兰)(基)(因)(、)(复)(宏)(汉)(霖)(、)(神)(州)(细)(胞)(、)(康)(宁)(杰)(瑞)(、)(华)(海)(药)(业)(、)(特)(瑞)(思)(药)(业)(、)(正)(大)(天)(晴)(等)(多)(家)(企)(业)(的)(贝)(伐)(珠)(单)(抗)(生)(物)(类)(似)(药)(已)(经)(进)(入)(临)(床)(三)(期)(。)(未)(来)(几)(年)(,)(贝)(伐)(珠)(单)(抗)(的)(市)(场)(竞)(争)(将)(非)(常)(激)(烈)(。)

(相)(关)(推)(荐) (博)(恩)(生)(物)(技)(术)(有)(限)(公)(司)(与)(武)(汉)(大)(学)(生)(命)(科)(学)(院)(洽)(谈)(合)(作) (日)(夜)(加)(班)(加)(点)(,)(紧)(急)(生)(产)(!)(珠)(海)(医)(疗)(企)(业)(新)(依)(科)(蓝)(氧)(科)(技)(向)(大)(湾)(区)(媒)(体)(捐)(赠)(防)(疫)(物)(资) (曹)(斌) (本)(文)(来)(源)(:)(新)(京)(报) (责)(任)(编)(辑)(:)(曹)(斌)_NA53

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